A question I hear a lot is: “Prem, do you have any suggestions for what to do when I’m playing with a lefty? “What I don’t hear quite so often is: “Prem, how do I play against a right-left combination?” and the reason I don’t hear it much is because a surprising number of players never even NOTICE when one of their opponents is left-handed (not to mention if both of them happen to be).